Arsenal - Reading
Kick-off: 15: 00 GMT.
TV: Highlights BBC ONE Match of the Day.
Arsenal (Possible, 4-2-3-1): Fabianski; Jenkinson; Mertesacker, Koscielny, Monreal; Arteta, Coquelin; Oxlade-Chamberlain, Cazorla, Ramsey; Giroud.
Out: Diaby (knee), Walcott (hip/thigh), Wilshere (ankle).
Test: Gibbs (virus).
Reading (Possible, 4-1-4-1): Taylor; Kelly, Pearce, Mariappa, Harte; Leigertwood; McCleary, Robson-Kanu, McAnuff, Karacan; Pogrebnyak.
Out: Federici (ankle), Roberts (hip).
Test: Kébé (groin).
Referee: Chris Foy. Matches: 19, R1 Y41.
Arsenal will be without England duo Jack Wilshere and Theo Walcott against Reading.
Midfielder Abou Diaby is also absent after being ruled out for nine months with anterior cruciate ligament damage in his left knee.
Left-back Kieran Gibbs will be assessed after being laid low by a virus, but striker Lukas Podolski (ankle) and right-back Bacary Sagna (knee) should be available again, while goalkeeper Wojciech Szczesny and captain Thomas Vermaelen are eyeing recalls.
Meanwhile, new Reading manager Nigel Adkins will have striker Pavel Pogrebnyak available again after a three-match suspension for the trip to Arsenal.
Former Arsenal trainee Stuart Taylor is likely to deputise again for goalkeeper Adam Federici, who has been sidelined with an ankle injury, while attacking midfielder Jimmy Kébé continues to battle against a groin problem.
Forward Jason Roberts remains sidelined.
There looks to be only one winner, with in-form Arsenal expected to brush aside struggling Reading comfortably.
Nigel Adkins, whose Southampton side lost 6-1 at Arsenal in September, has taken over a Royals side that lost five games in succession, while the Gunners have won four of their past five games and scored 12 goals in two victories at the Madejski Stadium earlier this season.